Learn how small mutations in non-coding DNA can alter sex development in rodents.

Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.

A study shows that changes in noncoding genes can trigger autoimmune diabetes in infants by affecting hundreds of immune-related genes, expanding understanding of genetic disease.

A single DNA letter, inserted into a stretch of the genome that doesn’t code for any protein, was enough to turn genetically ...

(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...

The genome has thousands of genes that code for proteins, which help carry out many of the cell's important functions. But ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...